IONS
Ionis Pharma (IONS) P/E Ratio
P/E Ratio as of Oct 29, 2026: -12.78
Average-12.64
Median-12.66
Minimum-13.07
Maximum-12.20
-12.78
0.43 (3.26%)past month
The P/E ratio for Ionis Pharma (IONS) is -12.78 as of Oct 29, 2026. This represents a decrease of -62.10% compared to its 12-month average P/E ratio of -33.72. A higher P/E ratio suggests that investors expect strong future earnings growth, while a lower P/E ratio may indicate a potentially undervalued stock or slowing growth.
Ionis Pharma P/E Ratio Formula = Stock Price ÷ Earnings Per Share (EPS)
Ionis Pharma’s P/E ratio represents the valuation of the company based on its earnings. It’s calculated by dividing the company’s latest stock price by its diluted earnings per share (EPS) over the past 12 months. The P/E ratio helps investors assess how much they are paying for each dollar of earnings, offering valuable insights when comparing Ionis Pharma to industry peers.
Ionis Pharma P/E Ratio Formula = Stock Price ÷ Earnings Per Share (EPS)
Ionis Pharma’s P/E ratio represents the valuation of the company based on its earnings. It’s calculated by dividing the company’s latest stock price by its diluted earnings per share (EPS) over the past 12 months. The P/E ratio helps investors assess how much they are paying for each dollar of earnings, offering valuable insights when comparing Ionis Pharma to industry peers.
Ionis Pharma (IONS) P/E Ratio Insights
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Ionis Pharma (IONS) P/E Ratio Historic Data
| Date | Stock price | P/E ratio |
|---|---|---|
| Oct 1, 2026 | $44.00 | -12.67 |
| Sep 1, 2026 | $59.88 | -17.24 |
| Aug 3, 2026 | $54.49 | -15.69 |
| Jul 1, 2026 | $79.19 | -37.67 |
| Jun 1, 2026 | $75.38 | -35.86 |
| May 1, 2026 | $75.28 | -35.81 |
| Apr 1, 2026 | $75.13 | -30.46 |
| Mar 2, 2026 | $81.96 | -33.23 |
| Feb 2, 2026 | $83.07 | -48.54 |
| Jan 2, 2026 | $79.67 | -46.56 |
Ionis Pharma (IONS) End of Year P/E Ratio
| Date | P/E ratio | Change |
|---|---|---|
| 2026 | -12.78 | -72.36% |
| 2025 | -46.23 | +223.06% |
| 2024 | -14.31 | -19.06% |
| 2023 | -17.68 | -93.99% |
| 2022 | -294.16 | +279.02% |
| 2021 | -77.61 | — |
FAQs About Ionis Pharma (IONS) P/E ratio
The latest P/E ratio of Ionis Pharma (IONS) is -12.78, as of Oct 29, 2026. This is calculated based on its current stock price and earnings per share (EPS).
Ionis Pharma’s last 12-month average P/E ratio is -33.72, compared to its current P/E ratio of -12.78. This reflects a decrease of -62.10%.
Ionis Pharma’s current P/E ratio of -12.78 is lower than its last 12-month average P/E of -33.72. A higher P/E can indicate strong future growth expectations, while a lower P/E might suggest undervaluation.
Ionis Pharma’s average P/E ratio over the last 3 years is -22.79. Comparing this to the current P/E helps assess recent valuation trends and whether the stock is trading above or below its mid-term historical range.
Ionis Pharma’s average P/E ratio over the last 5 years is -51.99. A deviation from this historical average may indicate shifts in growth expectations, profitability, or broader market conditions affecting valuation.
Ionis Pharma (IONS) P/E Ratio Insights
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