
Ionis Pharma (IONS) Stock Forecast & Price Target
Ionis Pharma (IONS) Analyst Ratings
Bulls say
Ionis Pharmaceuticals has demonstrated a strong financial outlook, raising its 2025 revenue guidance to $875-900 million, up from a previous estimate of $825-850 million, largely due to robust performance from its product portfolio and an unexpected revenue increase from Tryngolza. The company's positive momentum is further underscored by significant revenue contributions, such as $32 million for Tryngolza and a solid continuation of partnered programs, including Spinraza and Wainua, which also outperformed consensus forecasts. Additionally, Ionis's ongoing strategic initiatives, including the anticipated sNDA submission for olezarsen, enhance the company's market position by providing physicians and patients with greater dosing flexibility and convenience, reinforcing the overall bullish sentiment surrounding its pipeline and future growth potential.
Bears say
Ionis Pharmaceuticals has reported significant financial losses, with no expectation of profitability for several years, which raises concerns about its long-term viability. The company's cash and equivalents decreased slightly from $2.3 billion at the end of the second quarter of 2025 to $2.24 billion by the end of the third quarter, indicating potential liquidity issues amidst ongoing losses. Furthermore, multiple risks, including increased competition leading to market share erosion of Spinraza, delays in regulatory approvals, and the uncertainty surrounding the effectiveness of its drug candidates, contribute to a negative outlook on the company's ability to drive future growth and platform value.
This aggregate rating is based on analysts' research of Ionis Pharma and is not a guaranteed prediction by Public.com or investment advice.
Ionis Pharma (IONS) Analyst Forecast & Price Prediction
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