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SYRE
Volume: 13

SYRE Stock Forecast & Price Target

SYRE Analyst Ratings

Based on 6 analyst ratings
Strong Buy
Strong Buy 67%
Buy 33%
Hold 0%
Sell 0%
Strong Sell 0%

Bulls say

Spyre Therapeutics Inc is well-positioned in the biotechnology sector due to its innovative approach in developing biopharmaceutical products specifically targeting inflammatory bowel disease (IBD), which addresses a significant unmet medical need. Their lead candidate, SPY003, demonstrates promising therapeutic potential by effectively reducing treatment injection frequency and leveraging combination therapies, reinforcing its competitive advantage in the IBD treatment landscape. Additionally, positive industry commentary regarding the effectiveness of combination therapies in managing refractory IBD supports the broader market context for Spyre's pipeline, facilitating a favorable investment thesis.

Bears say

The analysis of Spyre Therapeutics Inc. suggests a challenging outlook due to the high immunogenicity rates associated with prior bispecific antibodies, which ranged from 72% to 100% in healthy volunteers. This concern around elevated immunogenicity may hinder the company's ability to effectively compete, especially when compared to alternatives such as JNJ-4804, which exhibited significantly lower rates of 6% in a Phase 2 patient population with ulcerative colitis. Furthermore, the difficulties in optimizing existing products for convenience could impede Spyre Therapeutics's progress in developing competitive therapies for inflammatory bowel disease.

SYRE has been analyzed by 6 analysts, with a consensus rating of Strong Buy. 67% of analysts recommend a Strong Buy, 33% recommend Buy, 0% suggest Holding, 0% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Spyre Therapeutics Inc and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Spyre Therapeutics Inc (SYRE) Forecast

Analysts have given SYRE a Strong Buy based on their latest research and market trends.

According to 6 analysts, SYRE has a Strong Buy consensus rating as of Feb 19, 2026. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $56.50, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $56.50, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Spyre Therapeutics Inc (SYRE)

Volume: 13

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