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PLRX Stock Forecast & Price Target

PLRX Analyst Ratings

Based on 15 analyst ratings
Buy
Strong Buy 20%
Buy 40%
Hold 40%
Sell 0%
Strong Sell 0%

Bulls say

Pliant Therapeutics Inc's primary product candidate, bexotegrast (PLN-74809), demonstrates promising efficacy in treating idiopathic pulmonary fibrosis (IPF) and primary sclerosing cholangitis (PSC), positioning it as a significant asset for the company. The novel dual blockade mechanism targeting integrins αvβ8 and αvβ1 is expected to enhance immune activation while potentially improving safety by minimizing systemic TGF-β side effects. The favorable evidence observed in early trials suggests that optimizing bexotegrast through additional dose-ranging studies could further support its development and market potential within the fibrosis treatment landscape.

Bears say

Pliant Therapeutics Inc. has recently terminated its BEACON-IPF Phase 2b trial for bexotegrast due to safety concerns, specifically an unexpected lower rate of IPF-related adverse events in the placebo group, signifying potential challenges for the drug's development. The cessation of this key trial raises significant concerns about the viability of bexotegrast as a treatment option, particularly as the company's pipeline appears limited with no clear catalysts expected in the near term. Additionally, Pliant reported a net loss of $49.7 million for Q4 2024, reflecting ongoing financial burdens amidst increasing uncertainty regarding the future of its only primary product candidate.

PLRX has been analyzed by 15 analysts, with a consensus rating of Buy. 20% of analysts recommend a Strong Buy, 40% recommend Buy, 40% suggest Holding, 0% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Pliant Therapeutics and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Pliant Therapeutics (PLRX) Forecast

Analysts have given PLRX a Buy based on their latest research and market trends.

According to 15 analysts, PLRX has a Buy consensus rating as of Jun 16, 2025. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $27.83, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $27.83, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Pliant Therapeutics (PLRX)


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