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KPTI
Volume: 1.75M
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Karyopharm Therapeutics (KPTI) Stock Forecast & Price Target

Karyopharm Therapeutics (KPTI) Analyst Ratings

Based on 17 analyst ratings
Buy
Strong Buy 29%
Buy 41%
Hold 24%
Sell 6%
Strong Sell 0%

Bulls say

Karyopharm Therapeutics is experiencing a favorable outlook due to the continued growth potential of XPOVIO (selinexor) in the multiple myeloma market, with projected out-year sales reaching approximately $500 million, thanks to recent indication expansions and the adoption of lower dosing strategies. The company's revenue stream is expected to stabilize around $120 million annually over the next decade, driven by a differentiated mechanism of action and increasing usage across both academic and community settings. Additionally, with a projected revenue of $115-$130 million in 2025, reflecting an 11% year-over-year growth, there remains significant upside potential if market uptake exceeds expectations.

Bears say

Karyopharm Therapeutics Inc faces significant commercial risks due to an increasingly competitive landscape in cancer therapies and the narrow therapeutic window associated with its primary product, XPOVIO, which may limit its market uptake. The company reported fourth quarter 2024 revenue of $30.5 million, slightly above estimates, yet still indicated ongoing financial challenges, exemplified by a negative EPS of ($0.24). Additionally, there are pipeline risks related to the potential failure of selinexor to gain FDA approval for certain indications, suggesting that setbacks in clinical programs could further threaten the company’s valuation, which is already affected by higher gross-to-net adjustments impacting revenue.

Karyopharm Therapeutics (KPTI) has been analyzed by 17 analysts, with a consensus rating of Buy. 29% of analysts recommend a Strong Buy, 41% recommend Buy, 24% suggest Holding, 6% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Karyopharm Therapeutics and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Karyopharm Therapeutics (KPTI) Forecast

Analysts have given Karyopharm Therapeutics (KPTI) a Buy based on their latest research and market trends.

According to 17 analysts, Karyopharm Therapeutics (KPTI) has a Buy consensus rating as of Jul 12, 2025. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $23.76, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $23.76, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Karyopharm Therapeutics (KPTI)

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