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KPTI
Volume: 63.07K
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Karyopharm Therapeutics (KPTI) Stock Forecast & Price Target

Karyopharm Therapeutics (KPTI) Analyst Ratings

Based on 5 analyst ratings
Buy
Strong Buy 20%
Buy 80%
Hold 0%
Sell 0%
Strong Sell 0%

Bulls say

Karyopharm Therapeutics is experiencing an upward revision in its valuation for the drug XPOVIO, with projected revenue for relapsed/refractory multiple myeloma (r/rMM) increasing to $130 million, alongside a significant increase in valuation for selinexor targeting TP53 wild-type endometrial cancer, now estimated at $73 million. The promising results from a Phase I study, demonstrating a 79% sustained virologic response and notable improvement in quality of life metrics, indicate potential for approval and revenue growth as data is anticipated in March 2026. Additionally, Karyopharm's ongoing evaluation of strategic alternatives, including potential mergers or sales, further supports a positive outlook for stockholder value maximization in both the short and long term.

Bears say

Karyopharm Therapeutics faces significant financial challenges, including a concerning inability to raise capital, which has led to a recent workforce reduction of approximately 20%. The company's current cash reserves of $70.3 million are projected to sustain operations until the first quarter of 2026, but this runway may be jeopardized by the myriad of risks associated with negative clinical data, delays in clinical development, and potential setbacks in regulatory approvals. Furthermore, the delayed top-line results from the Phase 3 trial of selinexor for myelofibrosis, not expected until 2026, exacerbates uncertainty regarding the company's future commercial success and may lead to long-term dilution risks for investors.

Karyopharm Therapeutics (KPTI) has been analyzed by 5 analysts, with a consensus rating of Buy. 20% of analysts recommend a Strong Buy, 80% recommend Buy, 0% suggest Holding, 0% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Karyopharm Therapeutics and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Karyopharm Therapeutics (KPTI) Forecast

Analysts have given Karyopharm Therapeutics (KPTI) a Buy based on their latest research and market trends.

According to 5 analysts, Karyopharm Therapeutics (KPTI) has a Buy consensus rating as of Oct 14, 2025. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $18.20, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $18.20, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Karyopharm Therapeutics (KPTI)

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