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KPTI
Volume: 16.99K
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Karyopharm Therapeutics (KPTI) Stock Forecast & Price Target

Karyopharm Therapeutics (KPTI) Analyst Ratings

Based on 17 analyst ratings
Buy
Strong Buy 29%
Buy 41%
Hold 24%
Sell 6%
Strong Sell 0%

Bulls say

Karyopharm Therapeutics Inc. is positioned favorably in the oncology market, particularly with its drug XPOVIO (selinexor), which has demonstrated high efficacy in treating multiple myeloma and is projected to achieve annual sales growth of approximately 11% reaching $115-$130 million in 2025. The company anticipates out-year sales from XPOVIO could grow to around $500 million due to expanded indications and increased adoption in both academic centers and community clinics, suggesting a robust and steady revenue stream. Furthermore, with its differentiated mechanism of action and the potential success of upcoming clinical trials, Karyopharm’s current enterprise value under $260 million presents an attractive investment opportunity.

Bears say

Karyopharm Therapeutics Inc faces significant commercial risks due to a crowded competitive landscape in the cancer therapeutics market, which may hinder the market uptake of its product XPOVIO (selinexor). The company reported fourth-quarter 2024 revenue of $30.5 million and a loss per share of $0.24, slightly better than estimates but still indicative of ongoing financial challenges. Additionally, the potential failure of selinexor in achieving FDA approval for p53 wild-type endometrial cancer and other pipeline setbacks could further negatively impact the company's valuation and stock performance.

Karyopharm Therapeutics (KPTI) has been analyzed by 17 analysts, with a consensus rating of Buy. 29% of analysts recommend a Strong Buy, 41% recommend Buy, 24% suggest Holding, 6% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Karyopharm Therapeutics and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Karyopharm Therapeutics (KPTI) Forecast

Analysts have given Karyopharm Therapeutics (KPTI) a Buy based on their latest research and market trends.

According to 17 analysts, Karyopharm Therapeutics (KPTI) has a Buy consensus rating as of Jun 16, 2025. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $25.47, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $25.47, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Karyopharm Therapeutics (KPTI)

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