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KPTI
Volume: 233.99K

Karyopharm Therapeutics (KPTI) Stock Forecast & Price Target

Karyopharm Therapeutics (KPTI) Analyst Ratings

Based on 6 analyst ratings
Buy
Strong Buy 33%
Buy 67%
Hold 0%
Sell 0%
Strong Sell 0%

Bulls say

Karyopharm Therapeutics Inc. has demonstrated significant progress with its lead drug, XPOVIO (selinexor), showing improved median progression-free survival (mPFS) of 39.5 months in patients with TP53 wild-type/pMMR tumors, which suggests strong efficacy in this subgroup. Additionally, the company's ongoing clinical trials, such as the XPORT-EC-042 trial, present potential for further label expansion of selinexor, which could drive future revenue growth. Improvements in overall survival (OS) metrics and total symptom scores (TSS) in recent studies indicate that selinexor may redefine standard of care and face limited competition, contributing to a positive outlook for the company's stock.

Bears say

Karyopharm Therapeutics Inc faces a negative outlook primarily due to its financial constraints and limited commercial success, particularly in multiple myeloma (MM), which has led to a declining valuation despite early promising data in myelofibrosis (MF). The company’s reliance on XPOVIO (selinexor) is undermined by risks including negative clinical data, slower clinical trial timelines, and the potential for setbacks in regulatory approvals and market uptake, all of which could hinder its revenue prospects. Further, recent valuations for XPOVIO suggest a downward revision in revenue forecasts, highlighting concerns about the therapy's market performance and the risk of long-term shareholder dilution.

Karyopharm Therapeutics (KPTI) has been analyzed by 6 analysts, with a consensus rating of Buy. 33% of analysts recommend a Strong Buy, 67% recommend Buy, 0% suggest Holding, 0% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Karyopharm Therapeutics and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Karyopharm Therapeutics (KPTI) Forecast

Analysts have given Karyopharm Therapeutics (KPTI) a Buy based on their latest research and market trends.

According to 6 analysts, Karyopharm Therapeutics (KPTI) has a Buy consensus rating as of Apr 23, 2026. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $14.67, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $14.67, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Karyopharm Therapeutics (KPTI)

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