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ALNY
Volume: 101

Alnylam Pharmaceuticals (ALNY) Stock Forecast & Price Target

Alnylam Pharmaceuticals (ALNY) Analyst Ratings

Based on 24 analyst ratings
Buy
Strong Buy 46%
Buy 38%
Hold 17%
Sell 0%
Strong Sell 0%

Bulls say

Alnylam Pharmaceuticals demonstrated strong financial performance in 2025, with combined net product revenues reaching approximately $2,987 million, exceeding initial guidance by over $800 million and reflecting an 81% year-over-year growth. The company's gross margin remained healthy, supported by expanded operating leverage, while its Rare franchise showed steady growth, representing a robust ~$500 million annual base and contributing to a combined revenue increase of approximately 18% year-over-year. Continued investment in R&D and growth in selling, general, and administrative expenses, projected at a 26% increase from 2025 to 2026, underscores Alnylam's commitment to expanding its portfolio and pipeline across various therapeutic areas.

Bears say

Alnylam Pharmaceuticals faces a negative outlook due to anticipated revenue declines, with management projecting a considerable reduction in 1Q26 growth compared to 4Q25, driven by transitory factors such as a $25 million decrease in international revenues due to a pricing reset in Germany and a mid-single-digit net price decline for Amvuttra in the U.S. Additionally, collaboration revenue is expected to drop significantly year-over-year in 2026, primarily resulting from the non-recurrence of a one-time $300 million milestone recorded in 2025, with guidance indicating a reduction in collaboration and royalty revenue from approximately $727 million in 2025 to an estimated $400 million to $500 million in 2026. The company’s financial health is further undermined by uncertainties related to regulatory approvals of its various therapeutic products, which could lead to downward revisions in financial projections if targets are not met.

Alnylam Pharmaceuticals (ALNY) has been analyzed by 24 analysts, with a consensus rating of Buy. 46% of analysts recommend a Strong Buy, 38% recommend Buy, 17% suggest Holding, 0% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Alnylam Pharmaceuticals and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Alnylam Pharmaceuticals (ALNY) Forecast

Analysts have given Alnylam Pharmaceuticals (ALNY) a Buy based on their latest research and market trends.

According to 24 analysts, Alnylam Pharmaceuticals (ALNY) has a Buy consensus rating as of Apr 2, 2026. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $468.79, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $468.79, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Alnylam Pharmaceuticals (ALNY)

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