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ALNY

Alnylam Pharmaceuticals (ALNY) Stock Forecast & Price Target

Alnylam Pharmaceuticals (ALNY) Analyst Ratings

Based on 24 analyst ratings
Buy
Strong Buy 46%
Buy 38%
Hold 17%
Sell 0%
Strong Sell 0%

Bulls say

Alnylam Pharmaceuticals demonstrated robust financial performance in 2025, with combined net product revenues reaching approximately $2.987 billion, a remarkable 81% increase year-over-year, thereby surpassing original revenue guidance by over $800 million. The company's successful growth in its Rare franchise—totaling around $500 million for the year—reflects strong demand for its therapeutic products such as GIVLAARI and OXLUMO, alongside improved gross margins and significant operating leverage expansion. Furthermore, Alnylam's strategic investments in research and development are expected to drive continued scale in its programs, substantiated by anticipated 26% year-over-year growth in combined R&D and SG&A expenses from 2025 to 2026, positioning the company well for future advancements in RNAi therapeutics.

Bears say

Alnylam Pharmaceuticals is facing a challenging financial outlook, primarily due to a forecasted decline in growth for 1Q26 attributed to transitory factors, which include international revenue reductions and pricing adjustments for AMVUTTRA. The company anticipates a significant drop in collaboration and royalty revenues in 2026, projected between $400 million and $500 million, down from approximately $727 million in 2025, which was bolstered by a one-time milestone payment. Additionally, ongoing gross-to-net dynamics coupled with tiered royalty escalations are expected to contribute to a mid-single-digit net price decline for AMVUTTRA, further straining revenue streams.

Alnylam Pharmaceuticals (ALNY) has been analyzed by 24 analysts, with a consensus rating of Buy. 46% of analysts recommend a Strong Buy, 38% recommend Buy, 17% suggest Holding, 0% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Alnylam Pharmaceuticals and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Alnylam Pharmaceuticals (ALNY) Forecast

Analysts have given Alnylam Pharmaceuticals (ALNY) a Buy based on their latest research and market trends.

According to 24 analysts, Alnylam Pharmaceuticals (ALNY) has a Buy consensus rating as of Apr 23, 2026. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $467.75, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $467.75, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Alnylam Pharmaceuticals (ALNY)


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