Protagonist Therapeutics

Protagonist Therapeutics, Inc. a clinical-stage biopharmaceutical company, discovers and develops peptide-based therapeutic drugs to address unmet medical needs. Its product pipeline include PTG-300, PTG-200, and PN-943 The company was founded by Mark L. Smythe on August 22, 2006 and is headquartered in Newark, CA.

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Protagonist Therapeutics, Inc. a clinical-stage biopharmaceutical company, which engages in discovering and developing peptide-based therapeutic drugs to address unmet medical needs. Its product pipeline includes PTG-300, PTG-200, and PN-943. The company was founded by Mark L. Smythe on August 22, 2006 and is headquartered in Newark, CA.

NEWARK, CA / ACCESSWIRE / October 3, 2023 / Protagonist Therapeutics, Inc. (NASDAQ:PTGX) today reported that on September 29, 2023, it issued inducement awards to Katharina Modelska, M.D., Ph.D., the Company's recently hired Senior Vice President, Clinical Development, in accordance with the terms of Dr. Modelska's employment offer letter.

Protagonist Therapeutics Reports Granting of Inducement Award

Protagonist Therapeutics, Inc.'s oral IL-23 drug for psoriasis, JNJ-2113, must show non-inferior efficacy to Johnson & Johnson's injectable Tremfya before further development. JNJ-2113 is the only oral IL-23 targeting molecule in development, but if it fails, it will join other abandoned Johnson & Johnson projects. Johnson & Johnson plans to proceed with a phase 3 trial for JNJ-2113 despite Tremfya's stronger numerical data, citing ease of administration and potential benefits for some patients.

Protagonist Therapeutics: There Are Reasons Behind Johnson & Johnson's Optimism

NEWARK, CA / ACCESSWIRE / September 5, 2023 / Protagonist Therapeutics, Inc. (NASDAQ:PTGX) ("Protagonist" or "the Company") today announced that Dinesh V. Patel, Ph.D.

Protagonist Therapeutics to Present at Upcoming Investor Conferences

Protagonist Therapeutics focuses on peptide-based drugs, primarily rusfertide, which is undergoing a Phase 3 trial for polycythemia vera. Financially, PTGX is robust with $313.4M in assets and a cash runway of ~31 months; rusfertide shows significant promise with positive REVIVE study results. Given PTGX's financial health and rusfertide's potential, I recommend a "Buy" but advise investor vigilance regarding future developments.

Protagonist Therapeutics: Evaluating Rusfertide's Potential For PV

Protagonist Therapeutics, Inc. is progressing with the use of its drug rusfertide for the treatment of polycythemia vera in a phase 3 study. The company expects to complete enrollment of the VERIFY study by Q1 2024 and release results in 2024. Protagonist Therapeutics has enough cash to fund its operations through the end of 2025 and could earn $200 million in milestone payments.

Protagonist: Rusfertide Has Potential For Patients With Polycythemia Vera

Estimated cash runway now extended through Q1 2026 NEWARK, CA / ACCESSWIRE / August 9, 2023 / Protagonist Therapeutics (NASDAQ:PTGX) ("Protagonist" or "the Company") today announced it has received approximately $34.4 million in proceeds from the exercise of warrants to purchase 2.75 million shares of the Company's Common Stock. The warrants were issued in connection with an August 2018 equity financing and expired on August 8, 2023.

Protagonist Receives $34 Million from Warrant Exercises

Positive topline results from the Phase 2b FRONTIER 1 study of JNJ-2113 (formerly PN-235), the first and only IL-23 receptor antagonist oral peptide drug candidate for the treatment of moderate-to-severe plaque psoriasis, presented at the World Congress of Dermatology. JNJ-2113 now advances toward a Phase 3 study in moderate-to-severe psoriasis and a Phase 2b study in ulcerative colitis.

Protagonist Reports Second Quarter 2023 Financial Results and Provides Corporate Update

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Phase 2b FRONTIER 1 data presentation at World Congress of Dermatology highlights that a greater proportion of patients achieved 75, 90 and 100 percent improvement in skin clearance at week 16 in comparison to placebo Phase 3 development in moderate-to-severe plaque psoriasis and Phase 2b development in ulcerative colitis are planned by Janssen NEWARK, CA / ACCESSWIRE / July 4, 2023 / Protagonist Therapeutics, Inc. ("Protagonist" or "the Company") today announced positive topline results from the Phase 2b FRONTIER 1 clinical trial evaluating the oral interleukin-23 receptor (IL-23R) antagonist JNJ-2113 (formerly PN-235) in adult patients with moderate-to-severe plaque psoriasis (PsO)[i] presented at World Congress of Dermatology in Singapore. The trial achieved all primary and secondary efficacy endpoints.

Protagonist Therapeutics Announces Positive Topline Results with JNJ-2113, the First and Only Oral IL-23 Receptor Antagonist Peptide in Development for Moderate-to-Severe Plaque Psoriasis

Protagonist Therapeutics (PTGX) made it through our "Recent Price Strength" screen and could be a great choice for investors looking to make a profit from stocks that are currently on the move.

Protagonist Therapeutics (PTGX) Is a Great Choice for 'Trend' Investors, Here's Why

The consensus price target hints at a 25.4% upside potential for Protagonist Therapeutics (PTGX). While empirical research shows that this sought-after metric is hardly effective, an upward trend in earnings estimate revisions could mean that the stock will witness an upside in the near term.

Wall Street Analysts Predict a 25.35% Upside in Protagonist Therapeutics (PTGX): Here's What You Should Know

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New drug approvals and pipeline progress are likely to help maintain momentum for the Zacks Biomedical and Genetics industry. A strong portfolio and a solid pipeline progress position PCVX, PTGX, LGND, MESO and PBYI well amid volatility.

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Here's Why Momentum in Protagonist Therapeutics (PTGX) Should Keep going

NEWARK, CA / ACCESSWIRE / June 9, 2023 / Protagonist Therapeutics, Inc. (NASDAQ:PTGX) ("Protagonist" or "the Company") announced today that Ronald Hoffman, MD, Icahn School of Medicine at Mount Sinai, provided a press briefing this morning on the late-breaking oral presentation abstract LB2710: Targeted Therapy of Uncontrolled Erythrocytosis in Polycythemia Vera with the Hepcidin Mimetic, Rusfertide - Blinded Randomized Withdrawal Results of the REVIVE Study at the European Hematology Association (EHA) 2023 Congress. The study results will be presented in detail by Marina Kremyanskaya, MD, PhD, Icahn School of Medicine at Mount Sinai, on Sunday, June 11, 2023 at 9:45-10:00 CEST.

Clinical Response and Durability of Response of Rusfertide (PTG-300) in Polycythemia Vera Featured Today at EHA Press Briefing; Protagonist Therapeutics Plans a Follow-on Two-Year Extension Study to Enable Further Evaluation of the Long-Term Effects of Ru

NEWARK, CA / ACCESSWIRE / June 6, 2023 / Protagonist Therapeutics, Inc. (NASDAQ:PTGX) ("Protagonist" or "the Company") today announced that a late-breaking abstract featuring blinded, randomized withdrawal data from the rusfertide (PTG-300) REVIVE Phase 2 study in polycythemia vera (PV) has been accepted for oral presentation at the European Hematology Association (EHA) 2023 Congress: Targeted Therapy of Uncontrolled Erythrocytosis in Polycythemia Vera with the Hepcidin Mimetic, Rusfertide - Blinded Randomized Withdrawal Results of the REVIVE Study: - Late Breaking Oral Presentation: Presented by Marina Kremyanskaya, MD, PhD, Icahn School of Medicine at Mount Sinai on Sunday, June 11, 9:45 - 10:00 CEST As previously announced, EHA will also feature two additional presentations from the Company's rusfertide peptide therapeutic development program, including new data and updates in polycythemia vera. Rusfertide (PTG-300) Improves (PV)-related Symptoms: - Presented by Andrew Kuykendall, MD, Moffitt Cancer Center on Friday, June 9, 18:00 - 19:00 CEST Pharmacokinetic and Pharmacodynamic Effects of Rusfertide in Polycythemia Vera: Results from an Ongoing Phase 2 Study in Patients with Elevated Hematocrit Values: - Presented by Marina Kremyanskaya, MD, PhD, Icahn School of Medicine at Mount Sinai on Friday, June 9, 18:00 - 19:00 CEST "We are very pleased to showcase a breadth of data at EHA demonstrating the tremendous promise for rusfertide to change the polycythemia vera treatment paradigm by potentially eliminating the need for phlebotomy, providing improvement of symptoms associated with PV, controlling erythrocytosis and ultimately achieving the treatment goal of maintaining hematocrit under 45% in step with current NCCN and ELN Clinical Practice Guidelines," said Arturo Molina, MD, MS, Chief Medical Officer, Protagonist Therapeutics.

Protagonist Therapeutics Announces Acceptance of Late-Breaking Abstract for Oral Presentation at 2023 European Hematology Association (EHA) Congress

NEWARK, CA / ACCESSWIRE / June 1, 2023 / Protagonist Therapeutics, Inc. (NASDAQ:PTGX) ("Protagonist" or "the Company") today announced that Dinesh V. Patel, Ph.D.

Protagonist Therapeutics to Participate in the 2023 Jefferies Healthcare Conference

The average of price targets set by Wall Street analysts indicates a potential upside of 38% in Protagonist Therapeutics (PTGX). While the effectiveness of this highly sought-after metric is questionable, the positive trend in earnings estimate revisions might translate into an upside in the stock.

How Much Upside is Left in Protagonist Therapeutics (PTGX)? Wall Street Analysts Think 38.01%

The stock of Protagonist Therapeutics, Inc. has more than doubled so far this year due to progress on a couple of fronts. Can the rally in the shares continue in 2023?

Protagonist Therapeutics Sees Steady If Bumpy Progress

Protagonist continues to quietly progress its pipeline, relying mainly on the polycythemia vera story to drive its business efforts. An ongoing phase 3 study will be the critical readout, but that doesn't mean that you need to wait for it.

Protagonist Therapeutics: All Quiet Heading Into An Important H2 2023

Data point to the potential of JNJ-2113 as a first-in-class drug candidate in multiple IL-23 driven-diseases NEWARK, Calif. , May 12, 2023 /PRNewswire/ -- Protagonist Therapeutics (Nasdaq: PTGX) ("Protagonist" or "the Company") reported data from its collaboration with Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson (Janssen), on Phase 1 and preclinical studies of JNJ-2113 (formerly PN-235), presented by Janssen and co-authored with Protagonist, as an oral presentation at the International Societies for Investigative Dermatology (ISID) 2023 meeting in Tokyo, Japan.

Protagonist Reports Positive Results from Phase 1 and Pre-clinical Studies of Oral Interleukin-23 Receptor Antagonist JNJ-2113

NEWARK, Calif. , May 11, 2023 /PRNewswire/ -- Protagonist Therapeutics, Inc. (Nasdaq: PTGX) ("Protagonist" or "the Company") today announced that Dinesh V.

Protagonist Therapeutics to Participate in the JMP Securities Life Sciences Conference

NEWARK, Calif. , May 11, 2023 /PRNewswire/ -- Protagonist Therapeutics (Nasdaq: PTGX) ("Protagonist" or "the Company") today announced that additional data from the REVIVE study of rusfertide in polycythemia vera will be presented in two posters at the annual Congress of the European Hematology Association (EHA), taking place June 8-11, 2023 in Frankfurt, Germany and virtually through June 15, 2023.

Protagonist Therapeutics Announces Presentations at the 2023 Annual Congress of the European Hematology Association

Shares of PTGX stock briefly broke out Friday after Protagonist said it plans to soon present new test results for its psoriasis drug. The post Protagonist, A Top 1% Biotech, Briefly Breaks Out On Psoriasis Enthusiasm appeared first on Investor's Business Daily.

Protagonist, A Top 1% Biotech, Briefly Breaks Out On Psoriasis Enthusiasm

Announced positive topline results from the Phase 2b FRONTIER 1 study of JNJ-2113 (formerly PN-235), a first-in-class oral peptide for the treatment of moderate-to-severe plaque psoriasis; additional data to be shared at medical conferences beginning in Q2 2023 Announced positive topline results from the randomized withdrawal portion of the Phase 2 REVIVE study of rusfertide in polycythemia vera (PV), with additional data to be shared at medical conferences beginning in Q2 2023 Extended cash runway through end of 2025 with the completion of an underwritten public offering of 5,750,000 shares with net proceeds of $108.1 million after deducting underwriting discounts and commissions NEWARK, Calif. , May 4, 2023 /PRNewswire/ -- Protagonist Therapeutics (Nasdaq: PTGX) ("Protagonist" or "the Company") today reported financial results for the first quarter ended March 31, 2023, and provided a corporate update.

Protagonist Reports First Quarter 2023 Financial Results and Provides Corporate Update

Protagonist Therapeutics could become a buyout target. The company's lead therapy is coming off promising results as a cancer treatment.

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